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TSPY1L Antibody

Catalog # Availability Size / Price Inquiry
APR06790G 0.1 mg / $695

TSPY1L Antibody

Brand

Leading Biology

Catalog Number

APR06790G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TSPY1L Antibody.

Molecular Weight

34 kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus

Host

Rabbit

Species Reactivity

Human, Mouse

Target

TSPY1; TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L.

Isotype

IgG

Symbol

TSPY

GeneID

UniProt ID

Function

May be involved in sperm differentiation and proliferation.

Summary

TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of TSPY1L in A20 cell lysate with TSPY1L antibody at (A) 0.5 and (B) 1 μg/mL

Specification

Quantity

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