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TSHZ1 Antibody

Catalog # Availability Size / Price Inquiry
APR06746G 0.1 mg / $695

TSHZ1 Antibody

Brand

Leading Biology

Catalog Number

APR06746G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TSHZ1 Antibody.

Molecular Weight

117916 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

TSHZ1;

Isotype

IgG

Symbol

SDCCAG33, TSH1

GeneID

UniProt ID

Function

Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).

Summary

TSHZ1 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of TSHZ1 in A-20 cell lysate with TSHZ1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of TSHZ1 in A20 cells with TSHZ1 antibody at 2.5 μg/mL.

Immunofluorescence of TSHZ1 in A20 cells with TSHZ1 antibody at 20 μg/mL.

Specification

Quantity

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