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ECRG1 Antibody

Catalog # Availability Size / Price Inquiry
APC00028G 0.1 mg / $695

ECRG1 Antibody

Brand

Leading Biology

Catalog Number

APC00028G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECRG1 Antibody.

Molecular Weight

47569 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Target

TMPRSS11A; At least two isoforms of ECRG1 are known to exist; ECRG1 antibody is predicted to not cross-react with other ECRG family members.

Isotype

IgY

Symbol

ECRG1, HATL1, HESP

GeneID

UniProt ID

Function

Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.

Summary

ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Specification

Quantity

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