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LY6K Antibody

Catalog # Availability Size / Price Inquiry
APR06715G 0.1 mg / $695

LY6K Antibody

Brand

Leading Biology

Catalog Number

APR06715G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LY6K Antibody.

Molecular Weight

18673 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

LY6K; Multiple isoforms of LY6K are known to exist.

Isotype

IgG

Symbol

CO16

GeneID

UniProt ID

Function

May play a role in cell growth.

Summary

LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 μg/mL.

Specification

Quantity

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