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NOD4 Antibody

Catalog # Availability Size / Price Inquiry
APR06663G 0.1 mg / $695

NOD4 Antibody

Brand

Leading Biology

Catalog Number

APR06663G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOD4 Antibody.

Molecular Weight

205 kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm

Host

Rabbit

Species Reactivity

Human, Mouse

Target

NLRC5; NOD4 antibody is predicted to not cross-react with other members of the NOD family of proteins.

Isotype

IgG

Symbol

NOD27, NOD4

GeneID

UniProt ID

Function

Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.

Summary

NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of NOD4 in EL4 cell lysate with NOD4 antibody at 1 μg/mL.

Immunocytochemistry of NOD4 in HeLa cells with NOD4 antibody at 10 μg/mL.

Immunofluorescence of NOD4 in HeLa cells with NOD4 antibody at 20 μg/mL.

Specification

Quantity

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