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SH3RF2 Antibody

Catalog # Availability Size / Price Inquiry
APR06660G 0.1 mg / $695

SH3RF2 Antibody

Brand

Leading Biology

Catalog Number

APR06660G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SH3RF2 Antibody.

Molecular Weight

79320 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

SH3RF2;

Isotype

IgG

Symbol

PPP1R39, RNF158

GeneID

UniProt ID

Function

Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function.

Summary

SH3RF2 Antibody: Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of SH3RF2 in human brain tissue with SH3RF2 antibody at 10 μg/mL.

Immunofluorescence of SH3RF2 in human brain tissue with SH3RF2 antibody at 20 μg/mL.

Specification

Quantity

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