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FREM1 Antibody

Catalog # Availability Size / Price Inquiry
APR06646G 0.1 mg / $695

FREM1 Antibody

Brand

Leading Biology

Catalog Number

APR06646G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FREM1 Antibody.

Molecular Weight

244154 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Localizes at the basement membrane zone of embryonic epidermis and hair follicles

Host

Rabbit

Species Reactivity

Human, Mouse

Target

FREM1;

Isotype

IgG

Symbol

C9orf143, C9orf145, C9orf154

GeneID

UniProt ID

Function

Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.

Summary

FREM1 Antibody: FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of FREM1 in K562 cell lysate with FREM1 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunocytochemistry of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL.

Immunofluorescence of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL.

Specification

Quantity

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