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CAZIP Antibody

Catalog # Availability Size / Price Inquiry
APR06609G 0.1 mg / $695

CAZIP Antibody

Brand

Leading Biology

Catalog Number

APR06609G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAZIP Antibody.

Molecular Weight

150195 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules

Host

Rabbit

Species Reactivity

Human, Mouse

Target

MTUS2;

Isotype

IgG

Symbol

CAZIP, KIAA0774, TIP150

GeneID

UniProt ID

Function

Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.

Summary

CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 μg/mL.

Immunofluorescence of CAZIP in mouse heart tissue with CAZIP antibody at 20 μg/mL.

Specification

Quantity

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