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STEAP2 Antibody

Catalog # Availability Size / Price Inquiry
APR06457G 0.1 mg / $695

STEAP2 Antibody

Brand

Leading Biology

Catalog Number

APR06457G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STEAP2 Antibody.

Molecular Weight

Predicted: 54 kDa Observed: 55 kDa

Cellular Localization

Antigen Cellular Localization: Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

STEAP2; This STEAP2 antibody does not cross-react with other STEAP proteins.

Isotype

IgG

Symbol

PCANAP1, STAMP1

GeneID

UniProt ID

Function

Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

Summary

STEAP2 Antibody: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of STEAP2 in human prostate tissue lysate with STEAP2 antibody at 1 μg/mL.

Immunohistochemistry of STEAP2 in human colon tissue with STEAP2 antibody at 2.5 μg/mL.

Immunofluorescence of STEAP2 in Human Colon cells with STEAP2 antibody at 20 μg/mL.

Specification

Quantity

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