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Sigma-1 Receptor Antibody

Catalog # Availability Size / Price Inquiry
APR00520G 50 μl / $695

Sigma-1 Receptor Antibody

Brand

Leading Biology

Catalog Number

APR00520G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Sigma-1 Receptor Antibody.

Molecular Weight

25128 Da

Host

Rabbit

Species Reactivity

Human, Mouse

GeneID

UniProt ID

Summary

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis of rat liver (lanes 1 and 3) and mouse liver (lanes 2 and 4) membranes:1, 2. Anti-Sigma-1 Receptor antibody (APR00520G), (1:200)3, 4. Anti-Sigma-1 Receptor antibody preincubated with the control peptide antigen.

Specification

Quantity

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