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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HORMAD2 antibody - N-terminal region

HORMAD2 antibody - N-terminal region

Catalog # Availability Size / Price Inquiry
APR01171G 50 μg / $545

HORMAD2 antibody - N-terminal region

Brand

Leading Biology

Catalog Number

APR01171G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HORMAD2 antibody - N-terminal region.

Molecular Weight

35kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes (By similarity)

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog

GeneID

UniProt ID

Function

Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

WB Suggested Anti-HORMAD2 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:62500 Positive Control: HT1080 cell lysate

Specification

Quantity

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