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SH3RF1 antibody - middle region

Catalog # Availability Size / Price Inquiry
APR00891G 50 μg / $545

SH3RF1 antibody - middle region

Brand

Leading Biology

Catalog Number

APR00891G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SH3RF1 antibody - middle region.

Molecular Weight

93kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cytoplasm. Golgi apparatus, trans- Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog

Symbol

KIAA1494, POSH, RNF142, SH3MD2

GeneID

UniProt ID

Function

Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent on it's RING domain, and hence it's E3 ligase activity.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

WB Suggested Anti-SH3RF1 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:312500 Positive Control: DU145 cell lysate

Specification

Quantity

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