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Polyclonal Antibodies >
FBXO7 antibody - middle regionBrand |
Leading Biology | Catalog Number |
APR00880G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FBXO7 antibody - middle region.
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Molecular Weight |
58kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Note=Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
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Symbol |
FBX7
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GeneID |
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UniProt ID |
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Function |
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IP
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Images |
Immunoprecipitation -- 5ug antibody WB Suggested Anti-FBXO7 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysateFBXO7 is supported by BioGPS gene expression data to be expressed in MCF7 FBXO7 antibody - middle region validated by WB using U2OS cells at 0.5μg/ml. |
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Specification |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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