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C6orf134 antibody - N-terminal regionBrand |
Leading Biology | Catalog Number |
APR00849G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality C6orf134 antibody - N-terminal region.
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Molecular Weight |
36kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Membrane, clathrin-coated pit {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348} Cell junction, focal adhesion {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Cell projection, axon {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton, spindle {ECO:0000255|HAMAP-Rule:MF_03130}
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
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GeneID |
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UniProt ID |
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Function |
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Required for normal sperm flagellar function. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
WB Suggested Anti-C6orf134 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: ACHN cell lysate |
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Specification |
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Quantity |
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