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IGFBP2 Antibody

AMM02664G Product Datasheet Protocol

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AMM02664G		100 μl / $545

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Leading Biology Inc.

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IGFBP2 Antibody

Brand	Leading Biology	Catalog Number	AMM02664G
Product Type	Monoclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IGFBP2 Antibody.
Molecular Weight	34814 Da
Cellular Localization	Antigen Cellular Localization: Secreted.
Host	Mouse
Species Reactivity	Human
Clone	1F6F6
Isotype	IgG1
Symbol	BP2, IBP2
GeneID	3485
UniProt ID	P18065
Function	Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC, E
Dilution	WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 ICC~~1:200~~1000 IF~~1:200~1000.
Images	Figure 1: Western blot analysis using IGFBP2 mouse mAb against truncated IGFBP2-His recombinant protein (1) and truncated IGFBP2 (aa40-328)-hIgGFc transfected CHO-K1 cell lysate (2). Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A), recturn(B), prostate (C), colon cancer (D) showing cytoplasmic localization using IGFBP2 mouse mAb with DAB staining. Figure 2: Immunofluorescence staining of methanol-fixed A431 (left) and Hela (right) cells showing cytoplasmic and membrane localization.
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