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Polyclonal Antibodies >
GJA1 / CX43 / Connexin 43 Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APG01238G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GJA1 / CX43 / Connexin 43 Antibody (C-Terminus).
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Molecular Weight |
43008 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
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Host |
Goat
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Species Reactivity |
Human, Mouse, Rat, Monkey, Dog
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Target |
Detects endogenous levels of total connexin 43.
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Isotype |
IgG
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Symbol |
GJAL
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GeneID |
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UniProt ID |
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Function |
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
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Summary |
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF
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Dilution |
IF (1:50 - 1:250), IHC-P (10 μg/ml), WB (1:500 - 1:2000),
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Images |
Anti-GJA1 / CX43 / Connexin 43 antibody IHC staining of human uterus, endometrium. Immunofluorescence. Immunostaining of primary RPE cells with CX43 antibody at 1:100 dilution. Western blot. |
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Specification |
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Quantity |
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