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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LEMD3 / MAN1 Antibody (C-Terminus)

LEMD3 / MAN1 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR03237G 50 μg / $495

LEMD3 / MAN1 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR03237G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LEMD3 / MAN1 Antibody (C-Terminus).

Molecular Weight

99997 Da

Cellular Localization

Antigen Cellular Localization: Nucleus inner membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

Human LEMD3. At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2

Symbol

MAN1

GeneID

UniProt ID

Function

Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.

Summary

Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (5 μg/ml), IHC-P (5 μg/ml), WB (1 μg/ml),

Images

Anti-LEMD3 / MAN1 antibody IHC staining of human kidney.

Immunofluorescence of LEMD3 in human colon tissue with LEMD3 antibody at 5 g/mL.

Western blot analysis of LEMD3 in human colon tissue lysate with LEMD3 antibody at 1 ug/ml.

Specification

Quantity

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