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SCUBE3 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR03057G 50 μg / $495

SCUBE3 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR03057G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCUBE3 Antibody (Internal).

Molecular Weight

109kDa

Cellular Localization

Antigen Cellular Localization: Secreted. Cell surface

Host

Rabbit

Species Reactivity

Human

Target

Human SCUBE3. At least two isoforms of SCUBE3 are known to exist. SCUBE3 antibody is predicted to not cross-react with other SCUBE members.

GeneID

UniProt ID

Function

Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.

Summary

Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Images

Anti-SCUBE3 antibody IHC staining of human pancreas.

Immunofluorescence of SCUBE3 in human kidney tissue with SCUBE3 antibody at 20 ug/ml.

Western blot analysis of SCUBE3 in mouse kidney tissue lysate with SCUBE3 antibody at (A) 1 and...

Specification

Quantity

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