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NLRX1 Antibody (aa580-630)

Catalog # Availability Size / Price Inquiry
APR02984G 50 μg / $495

NLRX1 Antibody (aa580-630)

Brand

Leading Biology

Catalog Number

APR02984G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NLRX1 Antibody (aa580-630).

Molecular Weight

108kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Monkey, Horse

Target

Human NLRX1

Symbol

NOD26, NOD5, NOD9

GeneID

UniProt ID

Function

Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Summary

Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5-10 μg/ml), WB (5-7 μg/ml),

Images

Western blot of NLRX1 in mouse heart tissue lysate in the 1) absence and 2) presence of...

Anti-NLRX1 antibody IHC of human heart.

Anti-NLRX1 antibody IHC of human skeletal muscle.

Specification

Quantity

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