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GATA4 Antibody (aa330-380)

Catalog # Availability Size / Price Inquiry
APR02979G 50 μg / $495

GATA4 Antibody (aa330-380)

Brand

Leading Biology

Catalog Number

APR02979G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GATA4 Antibody (aa330-380).

Molecular Weight

45kDa

Cellular Localization

Antigen Cellular Localization: Nucleus

Host

Rabbit

Species Reactivity

Human

Target

Human GATA4

GeneID

UniProt ID

Function

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.

Summary

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (1-3 μg/ml),

Images

Western blot of GATA-4 in human kidney lysate in the 1) absence and 2) presence of immunizing...

Anti-GATA4 antibody IHC of human brain, cortex.

Anti-GATA4 antibody IHC of human prostate.

Specification

Quantity

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