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CXXC5 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR02864G 50 μg / $495

CXXC5 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR02864G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CXXC5 Antibody (N-Terminus).

Molecular Weight

33kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.

Host

Rabbit

Species Reactivity

Human

Target

Human CXXC5. At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.

GeneID

UniProt ID

Function

May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.

Summary

May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Images

Immunofluorescence of CXXC5 in Human Brain cells with CXXC5 antibody at 20 ug/ml.

Western blot analysis of CXXC5 in human brain tissue lysate with CXXC5 antibody at 1 ug/ml.

Anti-CXXC5 antibody IHC of human pancreas.

Specification

Quantity

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