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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CDKN1C / p57 Kip2 Antibody (N-Terminus)

CDKN1C / p57 Kip2 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR03059G 50 μg / $495

CDKN1C / p57 Kip2 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR03059G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN1C / p57 Kip2 Antibody (N-Terminus).

Molecular Weight

32kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Target

Human CDKN1C / p57 Kip2. At least three isoforms of CDKN1C are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, CDKN1C often migrates at 57kD in SDS-PAGE. CDKN1C antibody is predicted to not cross ...

Symbol

KIP2

GeneID

UniProt ID

Function

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.

Summary

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Images

Anti-CDKN1C / p57 KIP2 antibody IHC staining of human skin.

Immunofluorescence of CDKN1C in 293 cells with CDKN1C antibody at 20 ug/ml.

Western blot analysis of CDKN1C in 293 cell lysate with CDKN1C antibody at (A) 1 and (B) 2 ug/ml.

Specification

Quantity

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