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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KIAA0517 / TRIM2 Antibody (C-Terminus)

KIAA0517 / TRIM2 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APG01128G 50 μg / $495

KIAA0517 / TRIM2 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APG01128G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIAA0517 / TRIM2 Antibody (C-Terminus).

Molecular Weight

82kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Goat

Species Reactivity

Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Chicken, Horse, Xenopus, Bovine, Dog

Target

Human TRIM2 / RNF86. This antibody is expected to recognise both reported isoforms (NP_056086.2; NP_001123539.1). Cross-reactivity with TRIM3 has been demonstrated.

Symbol

KIAA0517, RNF86

GeneID

UniProt ID

Function

UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.

Summary

UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:16000), IHC-P (6.25 μg/ml), WB (0.5-2 μg/ml)

Images

TRIM2 antibody (0.5 ug/ml) staining of Rat Brain lysate (35 ug protein/ml in RIPA buffer).

Anti-TRIM2 / RNF86 antibody IHC of human brain, cortex.

Specification

Quantity

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