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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PARD6A / PAR6 Antibody (C-Terminus)

PARD6A / PAR6 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APG01007G 50 μg / $495

PARD6A / PAR6 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APG01007G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PARD6A / PAR6 Antibody (C-Terminus).

Molecular Weight

37kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Note=Colocalizes with GTP- bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions

Host

Goat

Species Reactivity

Human

Target

Human PARD6A / PAR6. This antibody is expected to recognise both reported isoforms (NP_058644.1; NP_001032358.1).

Symbol

PAR6A

GeneID

UniProt ID

Function

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Summary

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, E

Dilution

ELISA (1:8000), IHC-P (5 μg/ml),

Images

Anti-PARD6A / PAR6 antibody IHC of human heart.

Specification

Quantity

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