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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10)

RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10)

Catalog # Availability Size / Price Inquiry
AMM01715G 50 μg / $495

RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10)

Brand

Leading Biology

Catalog Number

AMM01715G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10).

Molecular Weight

48kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human, Mouse

Target

The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.

Clone

11G10

Symbol

RBAP48

GeneID

UniProt ID

Function

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Summary

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, IP

Dilution

IHC-P (5 μg/ml)

Images

Anti-RBBP4 / RBAP48 antibody IHC of human testis.

Specification

Quantity

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