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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FCMR / FAIM3 Antibody (C-Terminus)

FCMR / FAIM3 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02365G 50 μg / $495

FCMR / FAIM3 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02365G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FCMR / FAIM3 Antibody (C-Terminus).

Molecular Weight

43kDa

Cellular Localization

Antigen Cellular Localization: Isoform 1: Membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Target

13 amino acid peptide from near the carboxy terminus of human Toso

Symbol

TOSO

GeneID

UniProt ID

Function

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Summary

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 μg/ml), WB (1 μg/ml),

Images

Anti-FAIM3 antibody IHC of human kidney.

Specification

Quantity

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