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Polyclonal Antibodies >
GRB4 / NCK2 Antibody (aa119-276)Brand |
Leading Biology | Catalog Number |
APR02353G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRB4 / NCK2 Antibody (aa119-276).
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Molecular Weight |
43kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Endoplasmic reticulum
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Amino acids 119 to 276 of human NCK2
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Symbol |
GRB4
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GeneID |
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UniProt ID |
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Function |
Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling.
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Summary |
Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P
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Dilution |
IHC-P (5 μg/ml)
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Images |
Anti-NCK2 antibody IHC of human brain, cerebellum. |
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Specification |
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Quantity |
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