> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AICDA / AID Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR02173G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AICDA / AID Antibody (C-Terminus).
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Molecular Weight |
24kDa
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic but shuttles between the nucleus and the cytoplasm
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
peptide corresponding to 14 amino acids near the carboxy-terminus of human AID
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Symbol |
AID
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GeneID |
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UniProt ID |
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Function |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
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Summary |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, ICC
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Dilution |
ICC (10 μg/ml), IHC-P (5 μg/ml), WB (1-2 μg/ml)
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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