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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MAS1 / MAS Antibody (Cytoplasmic Domain)

MAS1 / MAS Antibody (Cytoplasmic Domain)

Catalog # Availability Size / Price Inquiry
APR01974G 50 μg / $495

MAS1 / MAS Antibody (Cytoplasmic Domain)

Brand

Leading Biology

Catalog Number

APR01974G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAS1 / MAS Antibody (Cytoplasmic Domain).

Molecular Weight

37kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Hamster, Monkey, Pig, Bovine

Target

Human MAS1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Symbol

MAS

GeneID

UniProt ID

Function

Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Summary

Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (8-10 μg/ml)

Images

Anti-MAS1 / MAS antibody IHC of human Breast, Carcinoma.

Specification

Quantity

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