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Phospho-GATA1-S142 Antibody

Catalog # Availability Size / Price Inquiry
APR00477G 0.1 mg / $495

Phospho-GATA1-S142 Antibody

Brand

Leading Biology

Catalog Number

APR00477G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-GATA1-S142 Antibody.

Molecular Weight

42751 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

The antibody was affinity-purified from rabbit antiserum using epitope-specific phosphopeptide column, and the antibody against non-phosphopeptide was removed using non-phosphopeptide column corresponding to the phosphorylation site.

Isotype

Rabbit IgG

Symbol

ERYF1, GF1

GeneID

UniProt ID

Function

Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.

Summary

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IF

Dilution

WB~~1:500~1:1000 IHC~~1:50~1:100 IF~~1:100~200

Images

Western blot analysis of extracts from K562 cells using Phospho-GATA1-S142 Antibody (APR00477G).

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-GATA1-S142 Antibody (APR00477G).

Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-GATA1-S142 Antibody (APR00477G, Red).

Specification

Quantity

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