> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BPIFA1 / PLUNC Antibody (C-Term)Brand |
Leading Biology | Catalog Number |
APG00812G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BPIFA1 / PLUNC Antibody (C-Term).
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Molecular Weight |
26713 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Note=Apical side of airway epithelial cells. Detected in airway surface liquid, nasal mucus and sputum
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
LUNX, NASG, PLUNC, SPLUNC1, SPURT
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GeneID |
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UniProt ID |
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Function |
Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.
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Summary |
Reported variants represent identical protein: NP_057667.1, NP_001230122.1, NP_570913.1
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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