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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-RASSF7 / HRAS1 Antibody

Goat Anti-RASSF7 / HRAS1 Antibody

Catalog # Availability Size / Price Inquiry
APG00274G 0.1mg / $495

Goat Anti-RASSF7 / HRAS1 Antibody

Brand

Leading Biology

Catalog Number

APG00274G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-RASSF7 / HRAS1 Antibody.

Molecular Weight

39945 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Colocalizes with gamma-tubulin

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

C11orf13, HRC1

GeneID

UniProt ID

Function

Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00274G (1 μg/ml) staining of Jurkat cell lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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