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MMP-17 Antibody

Catalog # Availability Size / Price Inquiry
APR00126G 100 μg / $495

MMP-17 Antibody

Brand

Leading Biology

Catalog Number

APR00126G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP-17 Antibody.

Molecular Weight

66653 Da

Cellular Localization

Antigen Cellular Localization: Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

MMP17

Isotype

Rabbit IgG

Symbol

MT4MMP

GeneID

UniProt ID

Function

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Summary

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. MMP-17 (also designated MT-MMP4 or MT4-MMP) is a glycosylphosphatidylinositol (GPI)-anchored proteinase and is mainly expressed in the brain, leukocytes, colon, ovary and testis.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IP

Images

Specification

Quantity

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