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Bcl-3 Antibody

Catalog # Availability Size / Price Inquiry
APR00096G 100 μg / $495

Bcl-3 Antibody

Brand

Leading Biology

Catalog Number

APR00096G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Bcl-3 Antibody.

Molecular Weight

47584 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Ubiquitination via 'Lys- 63'-linked ubiquitin chains is required for nuclear accumulation

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Bcl-3

Isotype

Rabbit IgG

Symbol

BCL4, D19S37

GeneID

UniProt ID

Function

Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).

Summary

Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB-like molecule for native NFkB, but is specific for the p50 subunit of NFkB.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IP

Images

Specification

Quantity

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