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PF4 Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
AMM03908G 100 μg / $495

PF4 Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

AMM03908G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PF4 Antibody (monoclonal) (M01).

Molecular Weight

10845 Da

Host

mouse

Species Reactivity

Human

Target

PF4 (NP_002610, 31 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

3F6

Isotype

IgG1 Kappa

GeneID

UniProt ID

Summary

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IP, E

Dilution

WB~~1:500~1000

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33.55 KDa) .

Western Blot analysis of PF4 expression in transfected 293T cell line by PF4 monoclonal antibody (M01), clone 3F6.Lane 1: PF4 transfected lysate(10.8 KDa).Lane 2: Non-transfected lysate.

Immunoprecipitation of PF4 transfected lysate using anti-PF4 monoclonal antibody and Protein A Magnetic Bead (<a href="products_detail.asp?Catalog_id=U0007">U0007</a>), and immunoblotted with PF4 MaxPab rabbit polyclonal antibody.

Specification

Quantity

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