> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > PF4 Antibody (monoclonal) (M01)Brand |
Leading Biology | Catalog Number |
AMM03908G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PF4 Antibody (monoclonal) (M01).
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Molecular Weight |
10845 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
PF4 (NP_002610, 31 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
3F6
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Isotype |
IgG1 Kappa
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GeneID |
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UniProt ID |
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Summary |
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IP, E
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Dilution |
WB~~1:500~1000
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33.55 KDa) .
Western Blot analysis of PF4 expression in transfected 293T cell line by PF4 monoclonal antibody (M01), clone 3F6.Lane 1: PF4 transfected lysate(10.8 KDa).Lane 2: Non-transfected lysate.
Immunoprecipitation of PF4 transfected lysate using anti-PF4 monoclonal antibody and Protein A Magnetic Bead (<a href="products_detail.asp?Catalog_id=U0007">U0007</a>), and immunoblotted with PF4 MaxPab rabbit polyclonal antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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