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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CD20 / MS4A1 (B-Cell Marker) Antibody - Without BSA and Azide

CD20 / MS4A1 (B-Cell Marker) Antibody - Without BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM01524G 100 μg / $495

CD20 / MS4A1 (B-Cell Marker) Antibody - Without BSA and Azide

Brand

Leading Biology

Catalog Number

AMM01524G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD20 / MS4A1 (B-Cell Marker) Antibody - Without BSA and Azide.

Molecular Weight

33-37kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor

Host

Mouse

Species Reactivity

Human

Clone

109-3C2

Isotype

Mouse / IgG3, kappa

Symbol

CD20

GeneID

UniProt ID

Function

This protein may be involved in the regulation of B-cell activation and proliferation.

Summary

Recognizes a protein of 30-33kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IF, FC

Images

Specification

Quantity

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