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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide

CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM00923G 100 μg / $495

CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide

Brand

Leading Biology

Catalog Number

AMM00923G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide.

Molecular Weight

55kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Clone

143-13

Isotype

Mouse / IgG1, kappa

GeneID

UniProt ID

Function

Receptor for interleukin-2.

Summary

Recognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkinā€?s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ?? ? chain, p75) and CD132 (common ?? ? chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IF, FC

Images

Specification

Quantity

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