>
Antigen, Antibodies, ELISA, Western Blot >
Primary Antibody >
Monoclonal Antibodies >
Blood Group Antigen A (CD173) Antibody - Without BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00787G |
Product Type |
Monoclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Blood Group Antigen A (CD173) Antibody - Without BSA and Azide.
|
||
Molecular Weight |
Multiple KDa
|
||
Cellular Localization |
Antigen Cellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid
|
||
Host |
Mouse
|
||
Species Reactivity |
Human
|
||
Clone |
HE-193
|
||
Isotype |
Mouse / IgM, kappa
|
||
GeneID |
|||
UniProt ID |
|||
Function |
This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
|
||
Summary |
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
|
||
Form |
Liquid |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
IHC, IF
|
||
Images |
Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Blood Group Antigen A Monoclonal Antibody (HE-193) |
||
Specification |
|||
Quantity |
|
Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | AMM07977G | SPRY1 / Sprouty 1 Antibody (clone 3H4) | 50 μg | Monoclonal Antibodies |
|
$545.00 | Add Ask | ||
2 | Leading Biology | AMM00137G | CD79a (B-Cell Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
3 | Leading Biology | APG02467G | CCK4 / PTK7 Antibody (clone 4F9) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
4 | Leading Biology | AMM05365G | DC-SIGN Antibody [5D7] | 0.1 mg | Monoclonal Antibodies |
|
$695.00 | Add Ask | ||
5 | Leading Biology | AMM01402G | Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
6 | Leading Biology | APR08280G | LTA4H / LTA4 Antibody (clone 9G8) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask |
Complete this form and click send to ask us a question, request a quote or simply say hello.
You have 0 item in your cart
You have 0 item in your inquiry list