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FBXL5 antibody - middle region

Catalog # Availability Size / Price Inquiry
APR00877G 100 μg / $495

FBXL5 antibody - middle region

Brand

Leading Biology

Catalog Number

APR00877G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXL5 antibody - middle region.

Molecular Weight

76kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog

Symbol

FBL4, FBL5, FLR1

GeneID

UniProt ID

Function

Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Images

Human Muscle

WB Suggested Anti-FBXL5 Antibody Titration: 5.0μg/ml Positive Control: HepG2 cell lysate

Specification

Quantity

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