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PLA2G7 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR06200G 100 μl / $495

PLA2G7 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR06200G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLA2G7 Antibody (Center).

Molecular Weight

50077 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human

Immunogen

200-228 aa

Target

This PLA2G7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human PLA2G7.

Isotype

Rabbit Ig

Symbol

PAFAH

GeneID

UniProt ID

Function

Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

Summary

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

All lanes : Anti-PLA2G7 Antibody (Center) at 1:2000 dilution Lane 1: human liver lysate Lane 2: human lung lysate Lane 3: human spleen lysate Lane 4: human plasma lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of lysates from human liver and plasma tissue lysate (from left to right), using PLA2G7 Antibody (Center)(APR06200G). APR06200G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Western blot analysis of PLA2G7 Antibody (Center) (Cat. APR06200G) in HL-60 cell line lysates (35ug/lane). PLA2G7 (arrow) was detected using the purified Pab.

Specification

Quantity

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