> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NACC1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04758G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NACC1 Antibody (Center).
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Molecular Weight |
57258 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Distribution in the cytoplasm is dependent on phosphorylation.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
This NACC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 324-358 amino acids from the Central region of human NACC1.
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Isotype |
Rabbit Ig
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Symbol |
BTBD14B, NAC1
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GeneID |
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UniProt ID |
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Function |
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
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Summary |
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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