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PRDM1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR03968G 100 μl / $495

PRDM1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR03968G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRDM1 Antibody (N-term).

Molecular Weight

91771 Da

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

106-134 aa

Target

This PRDM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human PRDM1.

Isotype

Rabbit Ig

Symbol

BLIMP1

GeneID

UniProt ID

Function

Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).

Summary

This gene encodes a protein that acts as a repressor ofbeta-interferon gene expression. The protein binds specifically tothe PRDI (positive regulatory domain I element) of the beta-IFNgene promoter. Transcription of this gene increases upon virusinduction. Two alternatively spliced transcript variants thatencode different isoforms have been reported.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

PRDM1 Antibody (N-term) (Cat. APR03968G) western blot analysis in HL-60 cell line and mouse spleen tissue lysates (35ug/lane).This demonstrates the PRDM1 antibody detected the PRDM1 protein (arrow).

Specification

Quantity

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