> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PRDM1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03968G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRDM1 Antibody (N-term).
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Molecular Weight |
91771 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
106-134 aa
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Target |
This PRDM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human PRDM1.
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Isotype |
Rabbit Ig
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Symbol |
BLIMP1
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GeneID |
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UniProt ID |
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Function |
Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
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Summary |
This gene encodes a protein that acts as a repressor ofbeta-interferon gene expression. The protein binds specifically tothe PRDI (positive regulatory domain I element) of the beta-IFNgene promoter. Transcription of this gene increases upon virusinduction. Two alternatively spliced transcript variants thatencode different isoforms have been reported.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
PRDM1 Antibody (N-term) (Cat. APR03968G) western blot analysis in HL-60 cell line and mouse spleen tissue lysates (35ug/lane).This demonstrates the PRDM1 antibody detected the PRDM1 protein (arrow). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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