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Maspin Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03653G 100 μl / $495

Maspin Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03653G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Maspin Antibody (Center).

Molecular Weight

42100 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

94-123 aa

Target

This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.

Isotype

Rabbit Ig

Symbol

PI5

GeneID

UniProt ID

Function

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Summary

SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 IF~~1:10~50

Images

Western blot analysis of lysate from Hela cell line,using Maspin Antibody (Center)(Cat. APR03653G).APR03653G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.

Maspin Antibody (Center) (Cat. APR03653G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Maspin Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of Maspin Antibody (Center)( APR03653G) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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