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USP11 Antibody (C-term R565)

Catalog # Availability Size / Price Inquiry
AMM02484G 100 μl / $495

USP11 Antibody (C-term R565)

Brand

Leading Biology

Catalog Number

AMM02484G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USP11 Antibody (C-term R565).

Molecular Weight

109817 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Predominantly nuclear. Associates with chromatin

Host

Mouse

Species Reactivity

Human

Target

This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.

Clone

1220CT620.193.189

Isotype

IgG1,κ

Symbol

UHX1

GeneID

UniProt ID

Function

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.

Summary

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

FC~~1:25 WB~~1:1000

Images

Flow cytometric analysis of Hela cells using USP11 Antibody (C-term R565)(green, AMM02484G) compared to an isotype control of mouse IgG1(blue). AMM02484G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Western blot analysis of lysates from Jurkat, Hela, LNCaP cell line (from left to right) using USP11 Antibody (N-term) ( AMM02484G). AMM02484G was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.

Specification

Quantity

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