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Hira polyclonal antibody

Catalog # Availability Size / Price Inquiry
APR00449G 100 μl / $495

Hira polyclonal antibody

Brand

Leading Biology

Catalog Number

APR00449G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Hira polyclonal antibody.

Molecular Weight

111835 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence

Host

Rabbit

Species Reactivity

Mouse

Target

Hira

GeneID

UniProt ID

Function

Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Summary

Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Determination of the titer?

Western blot analysis using the antibody directed against Hira (1)?

Specification

Quantity

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