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FBXL5 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR06165G 100 μl / $495

FBXL5 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR06165G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXL5 Antibody (N-term).

Molecular Weight

78555 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

86-115 aa

Target

This FBXL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the N-terminal region of human FBXL5.

Isotype

Rabbit Ig

Symbol

FBL4, FBL5, FLR1

GeneID

UniProt ID

Function

Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in HepG2 cell line lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab;

Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in mouse heart tissue lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab.

FBXL5 Antibody (N-term) (Cat. APR06165G) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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