> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FBXL5 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR06165G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FBXL5 Antibody (N-term).
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Molecular Weight |
78555 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, perinuclear region
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
86-115 aa
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Target |
This FBXL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the N-terminal region of human FBXL5.
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Isotype |
Rabbit Ig
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Symbol |
FBL4, FBL5, FLR1
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GeneID |
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UniProt ID |
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Function |
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Images |
Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in HepG2 cell line lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab;
Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in mouse heart tissue lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab.
FBXL5 Antibody (N-term) (Cat. APR06165G) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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