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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Enterokinase/Enteropeptidase Antibody (C-term)

Enterokinase/Enteropeptidase Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR06078G 100 μl / $495

Enterokinase/Enteropeptidase Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR06078G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Enterokinase/Enteropeptidase Antibody (C-term).

Molecular Weight

112935 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

972-1002 aa

Target

This Enterokinase/Enteropeptidase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 972~1002 amino acids from the C-terminal region of human enteropeptidase.

Isotype

Rabbit Ig

Symbol

ENTK, PRSS7

GeneID

UniProt ID

Function

Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

Summary

This enzyme converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-Enteropeptidase Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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