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IGFALS Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05915G 100 μl / $495

IGFALS Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05915G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IGFALS Antibody (Center).

Molecular Weight

66035 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

308-335 aa

Target

This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.

Isotype

Rabbit Ig

Symbol

ALS

GeneID

UniProt ID

Function

Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

Summary

IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

Western blot analysis of IGFALS Antibody (Center) (Cat.APR05915G) in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35ug/lane). IGFALS (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

IGFALS Antibody (Center) (Cat. APR05915G) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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