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SERPINH1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05898G 100 μl / $495

SERPINH1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05898G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SERPINH1 Antibody (Center).

Molecular Weight

46441 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum lumen.

Host

Rabbit

Species Reactivity

Human

Immunogen

169-196 aa

Target

This SERPINH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the Central region of human SERPINH1.

Isotype

Rabbit Ig

Symbol

CBP1, CBP2, HSP47, SERPINH2

GeneID

UniProt ID

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

Summary

SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

Western blot analysis of SERPINH1 antibody (Center) (Cat. APR05898G) in HepG2 cell line lysates (35ug/lane). SERPINH1 (arrow) was detected using the purified Pab.

SERPINH1 Antibody (Center) (RB18952) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPINH1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

SERPINH1 Antibody (Center) (Cat. APR05898G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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