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CPN1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR05890G 100 μl / $495

CPN1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR05890G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CPN1 Antibody (N-term).

Molecular Weight

52286 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

52-81 aa

Target

This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CPN1.

Isotype

Rabbit Ig

Symbol

ACBP

GeneID

UniProt ID

Function

Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.

Summary

CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

All lanes : Anti-CPN1 Antibody (N-term) at 1:1000 dilution Lane 1: human liver lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of CPN1 antibody (N-term) (Cat.APR05890G) in K562, CEM, HEpG2 cell line lysates and mouse liver tissue lysates (35ug/lane). CPN1(arrow) was detected using the purified Pab.

Western blot analysis of CPN1 (arrow) using rabbit polyclonal CPN1 Antibody (N-term) (Cat. APR05890G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CPN1 gene.

Specification

Quantity

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